CKDdb-logoCKDdb - Molecule ID A5712

geneADAM19, MLTNB, FKSG34
nameADAM 19 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA19_HUMANQ9H013ENSG000001350748728Hs.483944603640

Functions and classifications

GOC:integral component of membrane, F:metalloendopeptidase activity, F:zinc ion binding, P:heart development, P:membrane protein ectodomain proteolysis, P:proteolysis, C:integral to membrane, F:metal ion binding
UniProtAlternative splicing, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, SH3-binding, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.110.02cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.00000419RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.00203RNA microarray19698090
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.380cDNA microarray21411733
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)2.81.69E-33NGS, RNA-seq.22266139
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.64< 0.05RNA-seq23757392
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.180.014118RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium