CKDdb-logoCKDdb - Molecule ID A5710

geneADAM15, MDC15
nameA disintegrin and metalloproteinase domain 15 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA15_HUMANQ13444ENSG000001435378751Hs.312098605548

Functions and classifications

GOC:acrosomal vesicle, C:adherens junction, C:cell projection, C:endomembrane system, C:integral component of membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:angiogenesis, P:cardiac epithelial to mesenchymal transition, P:cell-matrix adhesion, P:collagen catabolic process, P:proteolysis, P:tissue regeneration, P:integrin-mediated signaling pathway, C:extracellular region, C:flagellum, C:integral to membrane, F:metal ion binding
UniProtAlternative splicing, Angiogenesis, Cell adhesion, Cell junction, Cell projection, Cleavage on pair of basic residues, Collagen degradation, Complete proteome, Cytoplasmic vesicle, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Phosphoprotein, Polymorphism, Protease, Reference proteome, SH3-binding, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen, Integrin
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.130.0178RNA microarray19698090
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)1.52< 0.05LC-MS/MS24497609
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)5.660.003RNA microarray25770168

Compile date 08-10-2018© iMODE-CKD consortium