CKDdb-logoCKDdb - Molecule ID A5705

geneAcy3, Aspa2
nameN-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACY3_MOUSEQ91XE4ENSMUSG0000002486671670Mm.29735614413

Functions and classifications

GOC:apical plasma membrane, C:cytoplasm, C:membrane, F:aminoacylase activity, F:hydrolase activity, acting on ester bonds, F:identical protein binding, F:metal ion binding, F:protein binding
UniProt3D-structure, Cell membrane, Complete proteome, Cytoplasm, Hydrolase, Membrane, Metal-binding, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.350.01cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.340cDNA microarray19099603
Exp20959534Mus musculus kidneywholeDiabetes (type 2 diabetes)0.3< 0.05MALDI-TOF-MS20959534
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.37 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.46< 0.05RNA-seq23757392
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)18.010.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium