CKDdb-logoCKDdb - Molecule ID A5703

geneAcy1
nameAminoacylase-1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACY1_MOUSEQ99JW2ENSMUSG00000023262109652Mm.7165104620, 609924

Functions and classifications

GOC:cytoplasm, F:aminoacylase activity, F:metal ion binding, F:metallopeptidase activity, P:cellular amino acid metabolic process
UniProtComplete proteome, Cytoplasm, Hydrolase, Metal-binding, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.290.02cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.480.01cDNA microarray19099603
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.332.60E-04Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.363.50E-03Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.396.80E-04Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.43.00E-03Nano RP-LC, MALDI-TOF22061828
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)0.920.0419QSTAR Elite LC-MS/MS22172726
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.20.000273RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.350.00512RNA microarray23291264
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.43 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.5< 0.05RNA-seq23757392
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)0.5< 0.05LC-MS/MS24497609
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.270.00318RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium