CKDdb-logoCKDdb - Molecule ID A5698

geneACSM3, SAH, SA
nameAcyl-coenzyme A synthetase ACSM3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACSM3_HUMANQ53FZ2ENSG000000051876296Hs.706754145505

Functions and classifications

GOC:mitochondrial matrix, F:ATP binding, F:butyrate-CoA ligase activity, F:fatty acid ligase activity, F:metal ion binding, P:cholesterol homeostasis, P:fatty acid biosynthetic process, P:regulation of blood pressure, F:catalytic activity
UniProtAcetylation, Alternative splicing, ATP-binding, Complete proteome, Fatty acid metabolism, Ligase, Lipid metabolism, Magnesium, Metal-binding, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.0456RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.433.59E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.492.26E-05RNA microarray20019191
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.172.20E-05Nano RP-LC, MALDI-TOF22061828
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.428.36E-05NGS, RNA-seq.22266139
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.340.0000276RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium