CKDdb-logoCKDdb - Molecule ID A5690

geneAcsf2
nameAcyl-CoA synthetase family member 2, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACSF2_MOUSEQ8VCW8ENSMUSG00000076435264895Mm.386885610465

Functions and classifications

GOC:mitochondrion, F:ATP binding, F:ligase activity, P:fatty acid metabolic process
UniProtAcetylation, ATP-binding, Complete proteome, Fatty acid metabolism, Ligase, Lipid metabolism, Mitochondrion, Nucleotide-binding, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy) 2.11< 0.05LC-MS/MS  19845401
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis) 1.295.52E-06RNA microarray  20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy) down MS/MS, LTQ LX linear ion trap  20093355
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model) 0.62< 0.05LC-MS/MS  24497609
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 0.50.000119RNA microarray  24569379
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 17.140.012391RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium