CKDdb-logoCKDdb - Molecule ID A5689

geneAcss2, Acas2, Acecs1
nameAcetyl-coenzyme A synthetase, cytoplasmic
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACSA_MOUSEQ9QXG4ENSMUSG0000002760560525Mm.255026605832

Functions and classifications

GOC:cytoplasm, C:nucleus, F:acetate-CoA ligase activity, F:ATP binding, P:acetate biosynthetic process, P:acetyl-CoA biosynthetic process, P:propionate biosynthetic process, C:cytoplasm, F:acetate-CoA ligase activity, P:acetyl-CoA biosynthetic process, C:cytoplasm, C:nucleus, F:acetate-CoA ligase activity, P:acetate biosynthetic process, P:acetyl-CoA biosynthetic process, P:propionate biosynthetic process, C:cytoplasm, F:acetate-CoA ligase activity, P:acetyl-CoA biosynthetic process, C:cytoplasm, F:acetate-CoA ligase activity, P:acetyl-CoA biosynthetic process, C:cytoplasm, F:acetate-CoA ligase activity, P:acetyl-CoA biosynthetic process, C:cytoplasm, F:acetate-CoA ligase activity, P:acetyl-CoA biosynthetic process
UniProtAcetylation, ATP-binding, Complete proteome, Cytoplasm, Ligase, Nucleotide-binding, Phosphoprotein, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20926632aRattus norvegicus2kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)2.48< 0.05DNA microarray20926632
Exp20926632bRattus norvegicus2kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)1.92< 0.05DNA microarray20926632
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.43< 0.05RNA-seq23757392
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)0.244.55E-05LC-MS/MS24316357
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.390.000566RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium