CKDdb-logoCKDdb - Molecule ID A5688

geneACSS1, ACAS2L
nameAcetyl-coenzyme A synthetase 2-like
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACS2L_HUMANQ9NUB1ENSG0000015493084532Hs.529353614355

Functions and classifications

GOC:mitochondrial matrix, F:acetate-CoA ligase activity, F:AMP binding, F:ATP binding, P:acetate biosynthetic process, P:acetyl-CoA biosynthetic process, P:acetyl-CoA biosynthetic process from acetate, P:ethanol oxidation, P:propionate biosynthetic process, P:xenobiotic metabolic process, F:catalytic activity, P:metabolic process, C:mitochondrion
UniProt3D-structure, Acetylation, Alternative splicing, ATP-binding, Complete proteome, Direct protein sequencing, Ligase, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.350.01cDNA microarray  19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.310.01cDNA microarray  19099603
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy) 0.485.44E-05NGS, RNA-seq.  22266139
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model) 0.71< 0.05LC-MS/MS  24497609

Compile date 08-30-2016© iMODE-CKD consortium