CKDdb-logoCKDdb - Molecule ID A5681

geneAcox3
namePeroxisomal acyl-coenzyme A oxidase 3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACOX3_MOUSEQ9EPL9ENSMUSG0000002909880911Mm.291503603402

Functions and classifications

GOC:mitochondrion, C:peroxisomal matrix, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding, F:pristanoyl-CoA oxidase activity, P:fatty acid beta-oxidation, P:fatty acid beta-oxidation using acyl-CoA oxidase, C:mitochondrion, C:peroxisomal matrix, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding, F:pristanoyl-CoA oxidase activity, P:fatty acid beta-oxidation, C:mitochondrion, C:peroxisomal matrix, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding, F:pristanoyl-CoA oxidase activity, P:fatty acid beta-oxidation, C:mitochondrion, C:peroxisomal matrix, F:flavin adenine dinucleotide binding, F:pristanoyl-CoA oxidase activity, P:fatty acid beta-oxidation
UniProtComplete proteome, FAD, Fatty acid metabolism, Flavoprotein, Lipid metabolism, Oxidoreductase, Peroxisome, Phosphoprotein, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy) 2.599.49E-21NGS, RNA-seq.  22266139
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model) 08.67E-05LC-MS/MS  24316357
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 0.40.000642RNA microarray  24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 0.412.79E-04RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium