CKDdb-logoCKDdb - Molecule ID A5680

geneAcox2
namePeroxisomal acyl-coenzyme A oxidase 2
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACOX2_MOUSEQ9QXD1ENSMUSG0000002175193732Mm.28700601641

Functions and classifications

GOC:peroxisome, F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity, F:acyl-CoA dehydrogenase activity, F:acyl-CoA oxidase activity, F:flavin adenine dinucleotide binding, P:fatty acid beta-oxidation, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding, C:peroxisome, F:acyl-CoA dehydrogenase activity, F:acyl-CoA oxidase activity, F:flavin adenine dinucleotide binding, P:fatty acid beta-oxidation
UniProtAcetylation, Complete proteome, FAD, Fatty acid metabolism, Flavoprotein, Lipid metabolism, Oxidoreductase, Peroxisome, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies) 6.15< 0.05cDNA microarrays  17183245
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis) 1.583.59E-05RNA microarray  20019191
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy) 0.14< 0.05RNA-seq  23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy) 0.16< 0.05RNA-seq  23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 0.290.000222RNA microarray  24569379

Compile date 08-30-2016© iMODE-CKD consortium