CKDdb-logoCKDdb - Molecule ID A566E

geneCAV2, caveolin-2
nameCaveolin-2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAV2_HUMANP51636ENSG00000105971858Hs.212332601048

Functions and classifications

GOC:acrosomal membrane, C:caveola, C:cell surface, C:cytosol, C:extrinsic component of cytoplasmic side of plasma membrane, C:Golgi apparatus, C:Golgi membrane, C:integral component of plasma membrane, C:lipid particle, C:membrane, C:nucleus, C:perinuclear region of cytoplasm, C:protein complex, C:transport vesicle, F:protein homodimerization activity, P:caveola assembly, P:endoplasmic reticulum organization, P:mitochondrion organization, P:negative regulation of endothelial cell proliferation, P:negative regulation of transforming growth factor beta receptor signaling pathway, P:positive regulation of dopamine receptor signaling pathway, P:positive regulation of endothelial cell proliferation, P:protein oligomerization, P:regulation of mitosis, P:skeletal muscle fiber development, P:synaptic transmission, P:vesicle docking, P:vesicle fusion, C:extrinsic to internal side of plasma membrane, C:integral to plasma membrane
UniProtAlternative initiation, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, Golgi apparatus, Membrane, Nucleus, Phosphoprotein, Polymorphism, Reference proteome
PADBtransmembrane

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.320cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.00112RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.932.62E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.998.81E-05RNA microarray20019191
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL)2.120.0781RNA microarray20847290
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.74< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.16< 0.05RNA microarray21752957
Exp23291264aRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)2.720.003331RNA microarray23291264
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.468.70E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium