CKDdb-logoCKDdb - Molecule ID A5668

geneAcot12, Cach, Cach1
nameAcyl-coenzyme A thioesterase 12
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACO12_MOUSEQ9DBK0ENSMUSG0000002162074156Mm.275963614315

Functions and classifications

GOC:cytosol, F:acetyl-CoA hydrolase activity, F:ATP binding, F:lipid binding, P:acetyl-CoA metabolic process, P:fatty acid metabolic process, P:pyruvate metabolic process
UniProtComplete proteome, Cytoplasm, Fatty acid metabolism, Hydrolase, Lipid metabolism, Reference proteome, Repeat, Serine esterase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.370.03cDNA microarray19099603
Exp19688726aRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)2.83 MALDI-TOF19688726
Exp19688726bRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)5.66 MALDI-TOF19688726
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.31< 0.05RNA-seq23757392
Exp23757392cRattus norvegicus18kidneywholeDiabetes (diabetic nephropathy)0.39< 0.05RNA-seq23757392
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.018792802LC-MS/MS24172336
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.380.000305RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium