CKDdb-logoCKDdb - Molecule ID A5667

geneACOT11, BFIT, THEA
nameAcyl-coenzyme A thioesterase 11
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACO11_HUMANQ8WXI4ENSG0000016239026027Hs.745173606803

Functions and classifications

GOC:cytoplasm, F:acyl-CoA hydrolase activity, F:lipid binding, P:fatty acid metabolic process, P:intracellular signal transduction, P:response to cold, F:carboxylesterase activity
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Hydrolase, Polymorphism, Reference proteome, Repeat, Serine esterase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp17579666aMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model) 2.170.05RNA microarray  17579666
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.250.00055RNA microarray  19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 0.21< 0.05RNA microarray  21752957
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 0.490.00587RNA microarray  24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 7.726.88E-04RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium