CKDdb-logoCKDdb - Molecule ID A5667

geneACOT11, BFIT, THEA
nameAcyl-coenzyme A thioesterase 11
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACO11_HUMANQ8WXI4ENSG0000016239026027Hs.745173606803

Functions and classifications

GOC:cytoplasm, F:acyl-CoA hydrolase activity, F:lipid binding, P:fatty acid metabolic process, P:intracellular signal transduction, P:response to cold, F:carboxylesterase activity
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Hydrolase, Polymorphism, Reference proteome, Repeat, Serine esterase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17579666aMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)2.170.05RNA microarray17579666
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.00055RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.21< 0.05RNA microarray21752957
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.490.00587RNA microarray24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.726.88E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium