CKDdb-logoCKDdb - Molecule ID A5663

geneACMSD
name2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACMSD_HUMANQ8TDX5ENSG00000153086130013Hs.655728608889

Functions and classifications

GOC:cytosol, F:aminocarboxymuconate-semialdehyde decarboxylase activity, F:metal ion binding, P:quinolinate metabolic process, P:tryptophan catabolic process, F:catalytic activity
UniProt3D-structure, Alternative splicing, Complete proteome, Decarboxylase, Lyase, Metal-binding, Reference proteome, Zinc, Phosphoprotein
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.330cDNA microarray  19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.240cDNA microarray  19099603
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy) 0.48.30E-04Nano RP-LC, MALDI-TOF  22061828
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy) 0.450.015297805NGS, RNA-seq.  22266139
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity) 0.030.0000131RNA microarray  23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity) 0.150.0000473RNA microarray  23291264
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy) 0.48< 0.05RNA-seq  23757392

Compile date 08-30-2016© iMODE-CKD consortium