CKDdb-logoCKDdb - Molecule ID A5663

geneACMSD
name2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACMSD_HUMANQ8TDX5ENSG00000153086130013Hs.655728608889

Functions and classifications

GOC:cytosol, F:aminocarboxymuconate-semialdehyde decarboxylase activity, F:metal ion binding, P:quinolinate metabolic process, P:tryptophan catabolic process, F:catalytic activity
UniProt3D-structure, Alternative splicing, Complete proteome, Decarboxylase, Lyase, Metal-binding, Reference proteome, Zinc, Phosphoprotein
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.330cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.240cDNA microarray19099603
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.48.30E-04Nano RP-LC, MALDI-TOF22061828
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.450.015297805NGS, RNA-seq.22266139
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.030.0000131RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.150.0000473RNA microarray23291264
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.48< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium