CKDdb-logoCKDdb - Molecule ID A5656

geneAcads
nameShort-chain specific acyl-CoA dehydrogenase, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACADS_MOUSEQ07417ENSMUSG0000002954511409Mm.18759201470, 606885

Functions and classifications

GOC:mitochondrial matrix, C:mitochondrial membrane, C:mitochondrion, F:acyl-CoA dehydrogenase activity, F:butyryl-CoA dehydrogenase activity, F:fatty-acyl-CoA binding, F:flavin adenine dinucleotide binding, P:butyrate catabolic process, P:fatty acid beta-oxidation, P:fatty acid beta-oxidation using acyl-CoA dehydrogenase, P:protein homotetramerization, P:response to glucocorticoid, P:response to starvation, P:response to glucocorticoid stimulus, C:mitochondrion, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding
UniProt3D-structure, Acetylation, Complete proteome, Direct protein sequencing, FAD, Fatty acid metabolism, Flavoprotein, Lipid metabolism, Mitochondrion, Oxidoreductase, Reference proteome, Transit peptide, Complete proteome, FAD, Flavoprotein, Oxidoreductase, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy) down MS/MS, LTQ LX linear ion trap  20093355
Exp24172336Mus musculus6kidneycortexAKI (AKI) 1.360.022499604LC-MS/MS  24172336
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)   LC-MS/MS  24726496
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy) 2.850.02LC-MS/MS  24726496
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 9.940.005502RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium