CKDdb-logoCKDdb - Molecule ID A5652

geneACAD8, ARC42, IBD
nameAcyl-CoA dehydrogenase family member 8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACAD8_HUMANQ9UKU7ENSG0000015149827034Hs.14791604773, 611283

Functions and classifications

GOC:mitochondrial matrix, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding, P:branched-chain amino acid catabolic process, P:cellular nitrogen compound metabolic process, P:lipid metabolic process, P:regulation of transcription, DNA-templated, P:transcription, DNA-templated, P:valine catabolic process, F:flavin adenine dinucleotide binding, F:oxidoreductase activity, acting on the CH-CH group of donors, F:oxidoreductase activity, acting on the CH-CH group of donors, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProt3D-structure, Acetylation, Activator, Branched-chain amino acid catabolism, Complete proteome, Direct protein sequencing, Disease mutation, FAD, Flavoprotein, Mitochondrion, Oxidoreductase, Reference proteome, Transcription, Transcription regulation, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp23809614aHomo sapiens83bloodwholeChronic_Renal_Insufficiency (End-stage renal failure) 0.191.67E-14RNA microarray  23809614
Exp23809614bHomo sapiens32bloodwholeChronic_Renal_Insufficiency (End-stage renal failure) 0.141.83E-09RNA microarray  23809614
Exp24172336Mus musculus6kidneycortexAKI (AKI) 1.70.022499604LC-MS/MS  24172336

Compile date 08-30-2016© iMODE-CKD consortium