CKDdb-logoCKDdb - Molecule ID A5636

geneAPOBEC3B, APOBEC1L
nameApolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABC3B_HUMANQ9UH17ENSP000003274599582Hs.226307607110

Functions and classifications

GOC:nucleus, F:deoxycytidine deaminase activity, F:RNA binding, F:zinc ion binding, P:defense response to virus, P:innate immune response, P:negative regulation of transposition, F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, P:metabolic process, F:metal ion binding, P:metabolic process, P:negative regulation of transposition
UniProtAlternative splicing, Antiviral defense, Complete proteome, Hydrolase, Immunity, Innate immunity, Metal-binding, Nucleus, Polymorphism, Reference proteome, Repeat, RNA-binding, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.18< 0.05RNA microarray21752957
Exp25133636Homo sapiens22kidneyglomeruliGlomerulonephritis (IgA nephropathy (with endocapillary proliferation (E1)))2.650.0098RNA microarray25133636

Compile date 08-10-2018© iMODE-CKD consortium