CKDdb-logoCKDdb - Molecule ID A5586

geneBest5, Rsad2
nameRadical S-adenosyl methionine domain-containing protein 2
speciesRattus norvegicus

Molecule reference


Functions and classifications

GOC:endoplasmic reticulum, C:endoplasmic reticulum membrane, C:lipid particle, C:mitochondrial inner membrane, C:mitochondrial outer membrane, F:4 iron, 4 sulfur cluster binding, F:catalytic activity, F:metal ion binding, F:protein self-association, P:CD4-positive, alpha-beta T cell activation, P:CD4-positive, alpha-beta T cell differentiation, P:defense response to virus, P:innate immune response, P:negative regulation of protein secretion, P:negative regulation of viral genome replication, P:ossification, P:positive regulation of T-helper 2 cell cytokine production, P:positive regulation of toll-like receptor 7 signaling pathway, P:positive regulation of toll-like receptor 9 signaling pathway, P:regulation of ossification, P:response to virus, P:metabolic process, C:endoplasmic reticulum membrane, C:lipid particle, F:catalytic activity, F:iron-sulfur cluster binding, P:defense response to virus, P:metabolic process
UniProt4Fe-4S, Antiviral defense, Complete proteome, Endoplasmic reticulum, Immunity, Innate immunity, Iron, Iron-sulfur, Lipid droplet, Membrane, Metal-binding, Reference proteome, S-adenosyl-L-methionine,

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.350cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.470.01cDNA microarray19099603
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)18.110.00000576RNA microarray23291264

Compile date 08-10-2018© iMODE-CKD consortium