CKDdb-logoCKDdb - Molecule ID A5262

geneADAM18, TMDC3, UNQ858/PRO1867
nameADAM 18 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ADA18_HUMANQ9Y3Q7ENSG000001686198749Hs.127930

Functions and classifications

GOC:integral component of membrane, C:membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:cell differentiation, P:multicellular organismal development, P:proteolysis, P:spermatogenesis, C:integral to membrane
UniProtAlternative splicing, Complete proteome, Developmental protein, Differentiation, Disulfide bond, EGF-like domain, Glycoprotein, Membrane, Polymorphism, Reference proteome, Signal, Spermatogenesis, Transmembrane, Transmembrane helix
PADBdevelopment, cell growth, differentiation, morphogenesis

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.290.00656RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.282.12E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.130.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium