CKDdb-logoCKDdb - Molecule ID A518F

geneBOK, BCL2L9
nameBCL-2-related ovarian killer protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BOK_HUMANQ9UMX3ENSG00000176720666Hs.293753605404

Functions and classifications

GOC:mitochondrial outer membrane, C:nucleus, F:protein heterodimerization activity, F:protein homodimerization activity, P:activation of cysteine-type endopeptidase activity involved in apoptotic process, P:brain development, P:cell proliferation, P:extrinsic apoptotic signaling pathway in absence of ligand, P:intrinsic apoptotic signaling pathway by p53 class mediator, P:intrinsic apoptotic signaling pathway in response to DNA damage, P:male gonad development, P:neuron apoptotic process, P:oligodendrocyte differentiation, P:positive regulation of apoptotic process, P:positive regulation of execution phase of apoptosis, P:apoptotic process, P:regulation of apoptotic process, C:mitochondrion, C:mitochondrial membrane, P:induction of apoptosis
UniProtApoptosis, Complete proteome, Reference proteome
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.40.00216RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium