CKDdb-logoCKDdb - Molecule ID A5189

geneTubb2a, Tubb2
nameTubulin beta-2A chain
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
TBB2A_MOUSEQ7TMM9ENSMUSG0000005867222151Mm.422827615101

Functions and classifications

GOC:cytoplasm, C:microtubule, C:plasma membrane, F:GTP binding, F:GTPase activity, F:structural constituent of cytoskeleton, P:microtubule-based process, P:protein polymerization, F:peptide binding, F:structural molecule activity, P:microtubule-based movement, P:mitosis, P:neuron differentiation
UniProtComplete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, GTP-binding, Microtubule, Nucleotide-binding, Phosphoprotein, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.96< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)2.79< 0.05cDNA microarray17003339
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)7.84< 0.05cDNA microarrays17183245
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.120.04cDNA microarray19099603
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.130.03cDNA microarray19099603
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.33< 0.05RNA microarray21752957
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.66 nLC-ESI-UHR-QToF-MS/MS23344851

Compile date 08-10-2018© iMODE-CKD consortium