CKDdb-logoCKDdb - Molecule ID A509F

geneBMP5
nameBone morphogenetic protein 5 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BMP5_HUMANP22003ENSG00000112175653Hs.296648112265

Functions and classifications

GOC:extracellular space, C:membrane-bounded vesicle, F:cytokine activity, P:cartilage development, P:growth, P:male genitalia development, P:negative regulation of aldosterone biosynthetic process, P:negative regulation of cell proliferation, P:negative regulation of cortisol biosynthetic process, P:negative regulation of epithelial to mesenchymal transition, P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, P:negative regulation of insulin-like growth factor receptor signaling pathway, P:negative regulation of mononuclear cell migration, P:ossification, P:pattern specification process, P:positive regulation of dendrite development, P:positive regulation of DNA-dependent DNA replication, P:positive regulation of epithelial cell proliferation, P:positive regulation of pathway-restricted SMAD protein phosphorylation, P:positive regulation of transcription from RNA polymerase II promoter, P:skeletal system development, P:type B pancreatic cell development, C:extracellular region, P:negative regulation of apoptotic process
UniProtChondrogenesis, Cleavage on pair of basic residues, Complete proteome, Cytokine, Developmental protein, Differentiation, Disulfide bond, Glycoprotein, Growth factor, Osteogenesis, Polymorphism, Reference proteome, Secreted, Signal
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.280.00857RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium