CKDdb-logoCKDdb - Molecule ID A506F

geneBMI1, PCGF4, RNF51
nameBMI1 polycomb ring finger oncogene
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BMI1_HUMANP35226ENSG00000168283100532731Hs.380403164831

Functions and classifications

GOC:cytoplasm, C:nucleolus, C:PRC1 complex, C:ubiquitin ligase complex, F:zinc ion binding, P:chromatin modification, P:hemopoiesis, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of fibroblast proliferation, P:positive regulation of ubiquitin-protein ligase activity, P:segment specification, P:transcription, DNA-templated, C:nuclear body, F:chromatin binding, F:metal ion binding, F:sequence-specific DNA binding, F:ubiquitin-protein ligase activity, P:brain development, P:embryonic skeletal system morphogenesis, P:histone acetylation, P:histone ubiquitination, P:humoral immune response, P:in utero embryonic development, P:negative regulation of apoptotic process, P:positive regulation of B cell proliferation, P:positive regulation of immature T cell proliferation in thymus, P:rostrocaudal neural tube patterning, P:somatic stem cell division, P:transcription, DNA-dependent, C:PcG protein complex
UniProt3D-structure, Chromatin regulator, Complete proteome, Cytoplasm, Metal-binding, Nucleus, Polymorphism, Proto-oncogene, Reference proteome, Repressor, Transcription, Transcription regulation, Ubl conjugation, Zinc, Zinc-finger, Phosphoprotein
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.190.000228RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium