CKDdb-logoCKDdb - Molecule ID A506D

geneGPC1
nameGlypican-1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GPC1_HUMANP35052ENSG000000636602817Hs.328232600395

Functions and classifications

GOC:anchored component of membrane, C:endosome, C:extracellular space, C:Golgi lumen, C:integral component of plasma membrane, C:lysosomal lumen, C:membrane raft, C:proteinaceous extracellular matrix, F:copper ion binding, F:fibroblast growth factor binding, F:laminin binding, P:axon guidance, P:carbohydrate metabolic process, P:chondroitin sulfate metabolic process, P:glycosaminoglycan biosynthetic process, P:glycosaminoglycan catabolic process, P:heparan sulfate proteoglycan catabolic process, P:myelin assembly, P:negative regulation of fibroblast growth factor receptor signaling pathway, P:phototransduction, visible light, P:positive regulation of skeletal muscle cell differentiation, P:retinoid metabolic process, P:Schwann cell differentiation, C:anchored component of membrane, C:plasma membrane, C:anchored to membrane, C:integral to plasma membrane, P:Schwann cell differentiation
UniProt3D-structure, Cell membrane, Complete proteome, Copper, Direct protein sequencing, Disulfide bond, Endosome, Glycoprotein, GPI-anchor, Heparan sulfate, Lipoprotein, Membrane, Polymorphism, Proteoglycan, Reference proteome, S-nitrosylation, Secreted, Signal, Zinc
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.260.00127RNA microarray19698090
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.680.01447LC-MS/MS23228063
Exp24904088Mus musculus24kidneyglomeruliGlomerulonephritis (FSGS)0.614.04E-06RNA microarray24904088

Compile date 08-10-2018© iMODE-CKD consortium