CKDdb-logoCKDdb - Molecule ID A499J

geneADAMTS14
nameADAMTS-14 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS14_HUMANQ8WXS8ENSG00000138316140766Hs.352156607506

Functions and classifications

GOC:extracellular region, C:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:zinc ion binding, P:collagen catabolic process, P:collagen fibril organization, P:extracellular matrix organization, P:proteolysis, F:metal ion binding
UniProtAlternative promoter usage, Alternative splicing, Cleavage on pair of basic residues, Collagen degradation, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp22266139Homo sapienskidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.149.95E-20NGS, RNA-seq.22266139

Compile date 08-10-2018© iMODE-CKD consortium