CKDdb-logoCKDdb - Molecule ID A498F

geneBIRC7, KIAP, LIVIN
nameBaculoviral IAP repeat-containing protein 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BIRC7_HUMANQ96CA5ENSG0000010119779444Hs.256126605737

Functions and classifications

GOC:Golgi apparatus, C:nucleus, F:cysteine-type endopeptidase inhibitor activity, F:enzyme binding, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:activation of JUN kinase activity, P:apoptotic DNA fragmentation, P:negative regulation of apoptotic process, P:regulation of cell proliferation, P:regulation of natural killer cell apoptotic process, F:metal ion binding, C:intracellular
UniProt3D-structure, Alternative splicing, Apoptosis, Complete proteome, Cytoplasm, Golgi apparatus, Ligase, Metal-binding, Nucleus, Polymorphism, Protease inhibitor, Reference proteome, Thiol protease inhibitor, Ubl conjugation, Ubl conjugation pathway, Zinc, Zinc-finger
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.350.000106RNA microarray19698090
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)3.771.47E-15NGS, RNA-seq.22266139

Compile date 08-10-2018© iMODE-CKD consortium