CKDdb-logoCKDdb - Molecule ID A493J

geneADAM20
nameADAM 20 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA20_HUMANO43506ENSG000001340078748Hs.177984603712

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:binding of sperm to zona pellucida, P:multicellular organism reproduction, P:proteolysis, C:integral to membrane, F:metal ion binding, P:single fertilization
UniProtComplete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Protease, Reference proteome, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.230.000369RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.180.014348RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium