CKDdb-logoCKDdb - Molecule ID A489F

geneBEST3, VMD2L3
nameBestrophin-3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BEST3_HUMANQ8N1M1ENSG00000127325144453Hs.280782607337

Functions and classifications

GOC:chloride channel complex, C:plasma membrane, F:chloride channel activity, P:chloride transmembrane transport, P:negative regulation of ion transport
UniProtAlternative splicing, Calcium, Cell membrane, Chloride, Chloride channel, Complete proteome, Ion channel, Ion transport, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.182.98E-03RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.257.00E-04RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.294.50E-05RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.120.013999RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.140.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium