CKDdb-logoCKDdb - Molecule ID A479F

geneBCMO1, BCDO, BCDO1
nameBeta,beta-carotene 15,15'-dioxygenase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCDO1_HUMANQ9HAY6ENSG0000013569753630Hs.212172115300, 605748

Functions and classifications

GOC:cytosol, F:beta-carotene 15,15'-monooxygenase activity, F:metal ion binding, F:monooxygenase activity, P:phototransduction, visible light, P:retinal metabolic process, P:retinol metabolic process, P:vitamin A biosynthetic process, P:oxidation-reduction process, P:steroid metabolic process
UniProtAcetylation, Complete proteome, Disease mutation, Iron, Metal-binding, Monooxygenase, Oxidoreductase, Polymorphism, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.160.000162RNA microarray19698090
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.286.52E-05NGS, RNA-seq.22266139
Exp23757392cRattus norvegicus18kidneywholeDiabetes (diabetic nephropathy)3.61< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium