CKDdb-logoCKDdb - Molecule ID A477F

geneBCAR3, NSP2, SH2D3B
nameBreast cancer anti-estrogen resistance 3 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCAR3_HUMANO75815ENSG000001379368412Hs.36958604704

Functions and classifications

GOC:intracellular, F:guanyl-nucleotide exchange factor activity, P:regulation of GTPase activity, P:response to drug, P:signal transduction, P:small GTPase mediated signal transduction
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome, SH2 domain
PADBmodulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.490.01cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.410.01cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.380.00187RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.17< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)0.970.017620295LC-MS/MS24172336
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)4.831.93E-08RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium