CKDdb-logoCKDdb - Molecule ID A475F

geneBbs7, Bbs2l1
nameBardet-Biedl syndrome 7 protein homolog
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
BBS7_MOUSEQ8K2G4ENSMUSG0000003732571492Mm.286187

Functions and classifications

GOC:axoneme, C:BBSome, C:centrosome, C:ciliary basal body, C:ciliary membrane, C:nucleus, P:brain development, P:eye development, P:fat cell differentiation, P:heart development, P:limb development, P:nonmotile primary cilium assembly, P:palate development, P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process, P:protein localization, P:protein transport, P:regulation of transcription from RNA polymerase II promoter, P:smoothened signaling pathway, C:axoneme, C:BBSome, C:centrosome, C:ciliary basal body, C:nucleus, P:brain development, P:eye development, P:heart development, P:limb development, P:palate development, P:protein localization, P:smoothened signaling pathway, C:axoneme, C:BBSome, C:centrosome, C:ciliary basal body, C:nucleus, P:brain development, P:eye development, P:heart development, P:limb development, P:nonmotile primary cilium assembly, P:palate development, P:protein localization, P:smoothened signaling pathway, C:BBSome, P:nonmotile primary cilium assembly, C:BBSome, P:nonmotile primary cilium assembly, C:axoneme, C:BBSome, C:centrosome, C:ciliary basal body, C:nucleus, P:brain development, P:eye development, P:heart development, P:limb development, P:nonmotile primary cilium assembly, P:palate development, P:protein localization, P:smoothened signaling pathway
UniProtAcetylation, Alternative splicing, Cell membrane, Cell projection, Cilium, Cilium biogenesis/degradation, Complete proteome, Cytoplasm, Cytoskeleton, Membrane, Protein transport, Reference proteome, Transport
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)4.01< 0.05LC-MS/MS19845401
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.350.0000331RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium