CKDdb-logoCKDdb - Molecule ID A4750

geneDSTN, ACTDP, DSN
nameDestrin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
DEST_HUMANP60981ENSG0000012586811034Hs.304192609114

Functions and classifications

GOC:actin cytoskeleton, C:cortical actin cytoskeleton, P:actin filament depolymerization, P:actin filament severing, P:actin polymerization or depolymerization, P:cellular component movement, P:positive regulation of actin filament depolymerization, P:cytokinesis, C:intracellular
UniProtAcetylation, Actin-binding, Alternative splicing, Complete proteome, Direct protein sequencing, Phosphoprotein, Polymorphism, Reference proteome, Ubl conjugation
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.069.12E-08RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.53 nLC-ESI-UHR-QToF-MS/MS23344851

Compile date 08-10-2018© iMODE-CKD consortium