CKDdb-logoCKDdb - Molecule ID A472F

geneBbs2
nameBardet-Biedl syndrome 2 protein homolog
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
BBS2_MOUSEQ9CWF6ENSMUSG0000003175567378Mm.292107

Functions and classifications

GOC:BBSome, C:ciliary basal body, C:ciliary membrane, C:cytoplasm, C:motile cilium, P:adult behavior, P:artery smooth muscle contraction, P:brain morphogenesis, P:cartilage development, P:cerebral cortex development, P:cilium assembly, P:cilium morphogenesis, P:fat cell differentiation, P:Golgi to plasma membrane protein transport, P:hippocampus development, P:leptin-mediated signaling pathway, P:negative regulation of appetite by leptin-mediated signaling pathway, P:negative regulation of gene expression, P:negative regulation of multicellular organism growth, P:photoreceptor cell maintenance, P:positive regulation of multicellular organism growth, P:protein localization, P:protein localization to organelle, P:regulation of cilium beat frequency involved in ciliary motility, P:response to leptin, P:sperm axoneme assembly, P:striatum development, P:vasodilation, C:BBSome, C:ciliary basal body, P:adult behavior, P:artery smooth muscle contraction, P:brain morphogenesis, P:cartilage development, P:cerebral cortex development, P:cilium morphogenesis, P:hippocampus development, P:leptin-mediated signaling pathway, P:negative regulation of gene expression, P:negative regulation of multicellular organism growth, P:nonmotile primary cilium assembly, P:photoreceptor cell maintenance, P:positive regulation of multicellular organism growth, P:protein localization, P:response to leptin, P:sperm axoneme assembly, P:striatum development, P:vasodilation
UniProtCell membrane, Cell projection, Cilium, Cilium biogenesis/degradation, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Membrane, Protein transport, Reference proteome, Transport
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)20.6< 0.05LC-MS/MS19845401
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.310.0000305RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium