CKDdb-logoCKDdb - Molecule ID A469F

geneBAP1, hucep-6, HUCEP-6
nameUbiquitin carboxyl-terminal hydrolase BAP1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BAP1_HUMANQ92560ENSG000001639308314Hs.106674156240, 603089, 614327

Functions and classifications

GOC:cytoplasm, C:nucleolus, C:PR-DUB complex, F:chromatin binding, F:ubiquitin thiolesterase activity, F:ubiquitin-specific protease activity, P:monoubiquitinated histone H2A deubiquitination, P:negative regulation of cell proliferation, P:protein K48-linked deubiquitination, P:regulation of cell cycle, P:regulation of cell growth, P:ubiquitin-dependent protein catabolic process, C:intracellular
UniProtChromatin regulator, Coiled coil, Complete proteome, Cytoplasm, Hydrolase, Nucleus, Polymorphism, Protease, Reference proteome, Thiol protease, Ubl conjugation pathway
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.190.005591RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)9.420.003182RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium