CKDdb-logoCKDdb - Molecule ID A464F

geneBACH1, HA2303
nameTranscription regulator protein BACH1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BACH1_HUMANO14867ENSG00000156273571Hs.154276602751

Functions and classifications

GOC:nucleus, F:heme binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, F:sequence-specific DNA binding, P:regulation of transcription from RNA polymerase II promoter in response to hypoxia, P:regulation of transcription involved in G1/S transition of mitotic cell cycle, P:regulation of transcription involved in G2/M transition of mitotic cell cycle, F:DNA binding, F:sequence-specific DNA binding transcription factor activity, P:regulation of transcription involved in G1/S phase of mitotic cell cycle, P:regulation of transcription involved in G2/M-phase of mitotic cell cycle
UniProt3D-structure, Activator, Complete proteome, DNA-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18339188bHomo sapiens13bloodperipheral blood mononuclear cell (PBMC)Fabry (naive Fabry patients) 0.0394815microarray18339188
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.233.45E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium