CKDdb-logoCKDdb - Molecule ID A4636

geneCAPZA1
nameF-actin capping protein alpha-1 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAZA1_HUMANP52907ENSG00000116489829Hs.744974601580

Functions and classifications

GOC:cytosol, C:extracellular region, C:F-actin capping protein complex, C:WASH complex, F:actin binding, P:actin cytoskeleton organization, P:actin filament capping, P:blood coagulation, P:cellular component movement, P:innate immune response, P:protein complex assembly
UniProt3D-structure, Acetylation, Actin capping, Actin-binding, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.260.00000732RNA microarray19698090
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.93< 0.05RNA microarray21752957
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)0.190.000238477LC-MS/MS24316357
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.467.28E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium