CKDdb-logoCKDdb - Molecule ID A4634

geneCapg, Mbh1
nameMacrophage-capping protein
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAPG_MOUSEP24452ENSMUSG0000005673712332Mm.18626153615

Functions and classifications

GOC:extracellular region, C:melanosome, C:nucleus, P:actin filament capping, P:cell projection assembly, C:cytoplasm, C:nuclear membrane, C:nucleolus
UniProtAcetylation, Actin capping, Actin-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Nucleus, Phosphoprotein, Reference proteome, Repeat, Secreted
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19688726aRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)3.48 MALDI-TOF19688726
Exp19688726bRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)2.83 MALDI-TOF19688726
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp20940332Mus musculus kidneycollecting duct cellsVasopressine_induced (Vasopressine in vitro model)0.87< 0.05LC-MS/MS20940332
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)2.640cDNA microarray21411733
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.410cDNA microarray21411733
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.33< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.58< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.5< 0.05RNA-seq23757392
Exp23760282aMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)0.420.001RNA microarray23760282
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.458.26E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium