CKDdb-logoCKDdb - Molecule ID A4633

geneCAP1, CAP
nameAdenylyl cyclase-associated protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
CAP1_HUMANQ01518ENSP0000034483210487Hs.370581

Functions and classifications

GOC:cortical actin cytoskeleton, C:plasma membrane, P:actin cytoskeleton organization, P:activation of adenylate cyclase activity, P:ameboidal cell migration, P:axon guidance, P:establishment or maintenance of cell polarity, P:platelet activation, P:platelet degranulation, P:receptor-mediated endocytosis, P:signal transduction, P:cell morphogenesis, P:cytoskeleton organization
UniProt3D-structure, Acetylation, Actin-binding, Alternative splicing, Cell membrane, Complete proteome, Direct protein sequencing, Membrane, Phosphoprotein, Polymorphism, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.93< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.740.014321334LC-MS/MS24172336
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)1.960.013284069LC-MS/MS24316357

Compile date 08-10-2018© iMODE-CKD consortium