CKDdb-logoCKDdb - Molecule ID A4629

geneCALD1, CAD, CDM
nameCaldesmon
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CALD1_HUMANQ05682ENSG00000122786800Hs.490203114213

Functions and classifications

GOC:actin cap, C:actin cytoskeleton, C:cytosol, C:myofibril, C:plasma membrane, F:actin binding, F:calmodulin binding, F:tropomyosin binding, P:cellular component movement, P:muscle contraction, C:membrane, C:actin filament, C:neuronal cell body, C:postsynaptic density, P:actin filament bundle assembly, P:positive regulation of protein binding
UniProtActin-binding, Alternative splicing, Calmodulin-binding, Complete proteome, Cytoplasm, Cytoskeleton, Muscle protein, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19688726aRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)10.56 MALDI-TOF19688726
Exp19688726aRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)17.15 MALDI-TOF19688726
Exp19688726bRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)2.83 MALDI-TOF19688726
Exp19688726bRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)2.83 MALDI-TOF19688726
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)2.280.0480785RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.320.000425RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.320.00416RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.024RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.0253RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.033.59E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.320.000158024RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.533.23E-06RNA microarray20019191
Exp20940332Mus musculus kidneycollecting duct cellsVasopressine_induced (Vasopressine in vitro model)1.52< 0.05LC-MS/MS20940332
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)1.190.0089QSTAR Elite LC-MS/MS22172726
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.540.049147423LC-MS/MS24172336
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)0.470.043134612LC-MS/MS24316357

Compile date 08-10-2018© iMODE-CKD consortium