CKDdb-logoCKDdb - Molecule ID A461F

geneB4GALT7, XGALT1, UNQ748/PRO1478
nameBeta-1,4-galactosyltransferase 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
B4GT7_HUMANQ9UBV7ENSG0000002784711285Hs.455109130070, 604327

Functions and classifications

GOC:Golgi cisterna membrane, C:Golgi membrane, C:integral component of membrane, F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, F:manganese ion binding, F:xylosylprotein 4-beta-galactosyltransferase activity, P:chondroitin sulfate metabolic process, P:extracellular fibril organization, P:glycosaminoglycan biosynthetic process, P:negative regulation of fibroblast proliferation, P:protein N-linked glycosylation, F:transferase activity, transferring glycosyl groups, P:carbohydrate metabolic process, C:Golgi cisterna membrane, C:integral to membrane, F:metal ion binding, P:carbohydrate metabolic process, P:cellular protein modification process, P:protein glycosylation
UniProt3D-structure, Complete proteome, Disease mutation, Disulfide bond, Ehlers-Danlos syndrome, Glycoprotein, Glycosyltransferase, Golgi apparatus, Manganese, Membrane, Metal-binding, Reference proteome, Signal-anchor, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.00392RNA microarray19698090
Exp24189015aHomo sapiens5bloodmononuclear cellshealthy (healthy)3.64 +/- 0.17< 0.001RNA microarray24189015
Exp24189015bHomo sapiens9bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)4.04 +/- 0.34< 0.001RNA microarray24189015
Exp24189015cHomo sapiens10bloodmononuclear cellsDialysis (Peritoneal dialysis)3.38 +/- 0.39< 0.001RNA microarray24189015
Exp24189015dHomo sapiens17bloodmononuclear cellsDialysis (hemodialysis)3.42 +/- 0.24< 0.001RNA microarray24189015
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)5.420.010209RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium