CKDdb-logoCKDdb - Molecule ID A4587

geneASPN, PLAP1, UNQ215
nameAsporin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASPN_HUMANQ9BXN1ENSG0000010681954829Hs.435655603932, 607850, 608135

Functions and classifications

GOC:proteinaceous extracellular matrix, F:calcium ion binding, P:bone mineralization, P:negative regulation of tooth mineralization, P:negative regulation of transforming growth factor beta receptor signaling pathway
UniProtBiomineralization, Calcium, Complete proteome, Direct protein sequencing, Disulfide bond, Extracellular matrix, Glycoprotein, Leucine-rich repeat, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Triplet repeat expansion
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23760282aMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)0.170.017RNA microarray23760282
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)2.660.0049495RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium