CKDdb-logoCKDdb - Molecule ID A4584

geneArl8b
nameADP-ribosylation factor-like protein 8B
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ARL8B_MOUSEQ9CQW2ENSMUSG0000003010567166Mm.271178

Functions and classifications

GOC:cytoplasm, C:late endosome membrane, C:lysosomal membrane, C:midbody, C:spindle midzone, F:alpha-tubulin binding, F:beta-tubulin binding, F:GDP binding, F:GTP binding, F:GTPase activity, P:cell cycle, P:cell division, P:chromosome segregation, P:small GTPase mediated signal transduction, C:intracellular
UniProt3D-structure, Acetylation, Cell cycle, Cell division, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Endosome, GTP-binding, Lysosome, Membrane, Nucleotide-binding, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)2.2< 0.05LC-MS/MS19845401
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.120.045324529LC-MS/MS24172336
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)1.620.027939644LC-MS/MS24316357
Exp24927646aMus musculus16kidney Diabetes (diabetic nephropathy treated with Phlorizin)0.95< 0.05LC-MS/MS24927646
Exp24927646bMus musculus16kidney Diabetes (diabetic nephropathy)0.6< 0.05LC-MS/MS24927646
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.431.29E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium