CKDdb-logoCKDdb - Molecule ID A4581

geneARAP3, CENTD3
nameCentaurin-delta-3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARAP3_HUMANQ8WWN8ENSG0000012031864411Hs.726187606647

Functions and classifications

GOC:cytoskeleton, C:cytosol, C:lamellipodium, C:plasma membrane, C:ruffle, F:ARF GTPase activator activity, F:phosphatidylinositol-3,4,5-trisphosphate binding, F:phosphatidylinositol-3,4-bisphosphate binding, F:Rho GTPase activator activity, F:zinc ion binding, P:cytoskeleton organization, P:negative regulation of cell migration, P:negative regulation of Rac protein signal transduction, P:negative regulation of Rho protein signal transduction, P:regulation of ARF GTPase activity, P:regulation of cell shape, P:small GTPase mediated signal transduction, P:vesicle-mediated transport, C:intracellular, P:positive regulation of GTPase activity, P:signal transduction, F:metal ion binding, F:phospholipid binding
UniProt3D-structure, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, GTPase activation, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-finger
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.379.43E-08RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.233.23E-06RNA microarray20019191
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.480.0000199RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium