CKDdb-logoCKDdb - Molecule ID A4578

geneANXA8L1, ANXA8, ANX8
nameAnnexin A8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANXA8_HUMANP13928ENSG00000165390244Hs.535306602396

Functions and classifications

GOF:calcium ion binding, F:calcium-dependent phospholipid binding, P:blood coagulation
UniProt3D-structure, Annexin, Blood coagulation, Calcium, Calcium/phospholipid-binding, Complete proteome, Hemostasis, Metal-binding, Polymorphism, Reference proteome, Repeat
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18850734Canis lupus familiaris kidneydistal renal tubular cellskidney_calculi (Calcium oxalate monohydrate in vitro model)0.630.031Q-TOF MS/MS18850734
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.060.04cDNA microarray19099603
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)4.780.002051298NGS, RNA-seq.22266139
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)4.50.03107799LC-MS/MS24316357
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)24.422.63E-12RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)13.020.008335RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium