CKDdb-logoCKDdb - Molecule ID A4576

geneANXA5, ANX5, ENX2
nameAnnexin A5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANXA5_HUMANP08758ENSG00000164111308Hs.480653131230, 614391

Functions and classifications

GOC:cytoplasm, C:endothelial microparticle, C:external side of plasma membrane, C:extracellular vesicular exosome, F:calcium ion binding, F:calcium-dependent phospholipid binding, F:phospholipase inhibitor activity, P:blood coagulation, P:negative regulation of apoptotic process, P:negative regulation of coagulation, P:response to organic substance, P:signal transduction, C:cell projection, C:intercalated disc, C:sarcolemma, F:eukaryotic cell surface binding, P:positive regulation of apoptotic process, P:protein homooligomerization
UniProt3D-structure, Acetylation, Annexin, Blood coagulation, Calcium, Calcium/phospholipid-binding, Complete proteome, Direct protein sequencing, Hemostasis, Reference proteome, Repeat
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)1.5< 0.05MALDI-TOF-TOF17021608
Exp17609286Mus musculus10kidneyglomeruliDiabetes (diabetic nephropathy in Type 1 diabetes) < 0.05MALDI-TOF-MS17609286
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.090.00000632RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.12< 0.05RNA microarray21752957
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)1.19 nLC-ESI-UHR-QToF-MS/MS23344851
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)2.050.017225427LC-MS/MS24316357

Compile date 08-10-2018© iMODE-CKD consortium