CKDdb-logoCKDdb - Molecule ID A4575

geneANXA4, PIG28, ANX4
nameAnnexin A4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANXA4_HUMANP09525ENSG00000196975307Hs.422986106491

Functions and classifications

GOC:cytoplasm, F:calcium ion binding, F:calcium-dependent phospholipid binding, F:phospholipase inhibitor activity, P:negative regulation of apoptotic process, P:signal transduction, P:negative regulation of coagulation
UniProt3D-structure, Acetylation, Annexin, Calcium, Calcium/phospholipid-binding, Complete proteome, Direct protein sequencing, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)1.5< 0.05MALDI-TOF-TOF 17021608
Exp19369687Mus musculus kidneyproximal tubule cellsCyclosporine_A_induced (Ciclosporine A in vitro model)1.46< 0.04MALDI TOF/TOF 19369687
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.20.00000767RNA microarray 19698090
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)2.11< 0.05LC-MS/MS 19845401
Exp21538912aMus musculus10kidneyglomeruliglomerular_disease (glomerular disease)0.570.00035MALDI-TOF/TOF 21538912
Exp21538912bMus musculus8kidneyglomeruliglomerular_disease (glomerular disease)0.630.0089MALDI-TOF/TOF 21538912
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.38< 0.05RNA microarray 21752957
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.73 nLC-ESI-UHR-QToF-MS/MS 23344851
Exp24096133bHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy)1000 1DE, MALDI 24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)1000 1DE, MALDI 24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy)0 1DE, MALDI 24096133
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.370.032315097LC-MS/MS 24172336
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)1.590.006016463LC-MS/MSwestern blot 24316357
Exp24761003aRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.65< 0.05LC-MS/MS 24761003
Exp24761003bRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.79< 0.05LC-MS/MS 24761003
Exp24761003cRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.7< 0.05LC-MS/MS 24761003
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.333.33E-06RNA microarray 26317775

Compile date 08-10-2018© iMODE-CKD consortium