CKDdb-logoCKDdb - Molecule ID A4568

geneAMOT
nameAngiomotin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMOT_HUMANQ4VCS5ENSG00000126016154796Hs.528051300410

Functions and classifications

GOC:actin filament, C:cell surface, C:cytoplasm, C:cytosol, C:endocytic vesicle, C:external side of plasma membrane, C:integral component of membrane, C:lamellipodium, C:ruffle, C:stress fiber, C:tight junction, F:angiostatin binding, F:receptor activity, P:actin cytoskeleton organization, P:blood vessel endothelial cell migration, P:cell migration involved in gastrulation, P:cell-cell junction assembly, P:cellular protein localization, P:chemotaxis, P:establishment of cell polarity involved in ameboidal cell migration, P:gastrulation with mouth forming second, P:hippo signaling, P:in utero embryonic development, P:negative regulation of angiogenesis, P:negative regulation of GTPase activity, P:negative regulation of vascular permeability, P:positive regulation of blood vessel endothelial cell migration, P:positive regulation of cell size, P:positive regulation of embryonic development, P:positive regulation of stress fiber assembly, P:regulation of cell migration, P:regulation of small GTPase mediated signal transduction, P:vasculogenesis, C:cytoplasmic vesicle, C:integral to membrane, P:hippo signaling cascade
UniProtAlternative splicing, Cell junction, Coiled coil, Complete proteome, Phosphoprotein, Reference proteome, Tight junction, Ubl conjugation
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.0304RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.34< 0.05RNA microarray21752957
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.327.64E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.170.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium