CKDdb-logoCKDdb - Molecule ID A4556

geneADAM2, FTNB
nameADAM 2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADAM2_HUMANQ99965ENSG000001047552515Hs.177959601533

Functions and classifications

GOC:cell surface, C:integral component of plasma membrane, F:integrin binding, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:adult behavior, P:binding of sperm to zona pellucida, P:cell adhesion, P:fusion of sperm to egg plasma membrane, P:proteolysis, P:visual learning, C:extracellular region, P:integrin-mediated signaling pathway, C:acrosomal vesicle, C:integral to plasma membrane
UniProtAlternative splicing, Cell adhesion, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Membrane, Polymorphism, Reference proteome, Signal, Transmembrane, Transmembrane helix, Integrin
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.38.87E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium