CKDdb-logoCKDdb - Molecule ID A4555

nameActin, alpha skeletal muscle
speciesHomo sapiens

Molecule reference

ACTS_HUMANP68133ENSG0000014363258Hs.1288102610, 161800, 255310

Functions and classifications

GOC:actin filament, C:cytosol, C:extracellular vesicular exosome, C:stress fiber, C:striated muscle thin filament, F:ADP binding, F:ATP binding, F:myosin binding, F:structural constituent of cytoskeleton, P:cell growth, P:muscle filament sliding, P:response to extracellular stimulus, P:response to lithium ion, P:response to mechanical stimulus, P:response to steroid hormone, P:skeletal muscle fiber adaptation, P:skeletal muscle fiber development, P:skeletal muscle thin filament assembly, C:cytoplasm, C:cytoskeleton, P:response to steroid hormone stimulus
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Methylation, Muscle protein, Nemaline myopathy, Nucleotide-binding, Oxidation, Reference proteome, Phosphoprotein
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp21595033aHomo sapiens12urineexosomesGlomerulonephritis (IgA nephropathy) 0.020.03481LC-MS/MS  21595033
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy) 2.540.011359637NGS, RNA-seq.  22266139
Exp24798088Rattus norvegicus kidney AKI (AKI) 0.280.05MS/MS  24798088
Exp25279147Homo sapiens12kidneybiopsy sectionGlomerulonephritis (IgA nephropathy) 2.76< 0.05MALDI TOF/TOF  25279147

Compile date 08-30-2016© iMODE-CKD consortium