CKDdb-logoCKDdb - Molecule ID A4547

geneACTA2, ACTSA, ACTVS
nameActin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTA_HUMANP62736ENSG0000010779659Hs.500483102620, 611788, 613834, 614042

Functions and classifications

GOC:actin cytoskeleton, C:cytosol, C:protein complex, C:smooth muscle contractile fiber, F:ATP binding, P:glomerular mesangial cell development, P:muscle contraction, P:regulation of blood pressure, P:response to virus, P:vascular smooth muscle contraction, C:cell periphery, C:cytoplasm, C:cytoskeleton
UniProtAcetylation, Aortic aneurysm, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Methylation, Muscle protein, Nucleotide-binding, Oxidation, Polymorphism, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp16316330bRattus norvegicus10kidneycortexGlomerulonephritis (Thy_1_nephritis) 18.38< 0.01cDNA microarray  16316330
Exp16316330cRattus norvegicus10kidneycortexGlomerulonephritis (Thy_1_nephritis) 4.92< 0.01cDNA microarray  16316330
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.290.0128RNA microarray  19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis) 4.723.23E-06RNA microarray  20019191
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection) 0.3 LC-MS/MS  20543976
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis) 2.020.001cDNA microarray  21411733
Exp24096133aHomo sapiens10urine>10kDaDiabetes (type 1 diabetes without retinopathy or nephropathy) 1000 1DE, MALDI  24096133
Exp24096133cHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy) 1000 1DE, MALDI  24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy) 0 1DE, MALDI  24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy) 0.48 1DE, MALDI  24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy) 1000 1DE, MALDI  24096133

Compile date 08-30-2016© iMODE-CKD consortium